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143 Malaria is a major cause of anaemia in endemic areas and is one of the most common reasons for blood transfusion in areas of high transmission

Moreover, there is currently a lack of well-established biomarkers for ferroptosis, making it difficult to monitor in real time whether therapeutic agents have successfully activated ferroptosis pathways in clinical settings, which constitutes one of the major bottlenecks in clinical trial design (139)

Research into these indications is expanding the understanding of how weight reduction interacts with mechanical and inflammatory disease processes

Tsukasaki and Takayanagi, 2019)